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EGCG IV Therapy: Cellular Protection and Anti-Inflammatory Power from Green Tea Extract

Epigallocatechin gallate (EGCG), the most potent catechin found in green tea, is increasingly recognized for its profound antioxidant, anti-inflammatory, and metabolic benefits.

While traditionally consumed in tea or supplement form, EGCG IV Therapy delivers this powerful compound directly into the bloodstream for superior absorption and therapeutic effect.

At Live More Clinic, we offer EGCG IV as part of our advanced cellular wellness programs, targeting inflammation, detoxification, and chronic metabolic stress.

What Is EGCG (Epigallocatechin gallate)?

EGCG (Epigallocatechin gallate) is the most biologically active polyphenol in green tea, responsible for many of its health-promoting properties. In the body, EGCG acts as a strong antioxidant and inflammation modulator, helping neutralize free radicals, suppress pro-inflammatory cytokines, and support detoxification pathways at the cellular level.

Because EGCG has poor oral bioavailability, intravenous administration allows for significantly higher blood concentrations, making it a promising adjunctive therapy for oxidative stress, immune dysregulation, and chronic inflammatory conditions.

Key Benefits of EGCG IV Therapy

 
Potent Anti-Inflammatory Action

EGCG inhibits key inflammatory mediators such as NF-κB and COX-2, helping to reduce systemic inflammation. This is especially beneficial for patients with autoimmune conditions, chronic pain, or inflammatory skin disorders.

Antioxidant and Cellular Protection

As a scavenger of free radicals, EGCG protects DNA, lipids, and proteins from oxidative damage, slowing the aging process and reducing the risk of chronic diseases such as cardiovascular disease and cancer.

Support for Metabolic Health and Weight Regulation

EGCG has been shown to improve insulin sensitivity, regulate blood sugar levels, and enhance fat metabolism. It may be used to complement programs targeting metabolic syndrome, fatty liver, or type 2 diabetes.

Detoxification and Liver Support

EGCG enhances phase II liver detoxification enzymes and helps reduce hepatic inflammation, making it a valuable therapy for those undergoing detox, managing liver conditions, or exposed to high environmental toxin loads.

Neuroprotective Properties

Emerging research suggests EGCG may help reduce neuroinflammation and oxidative stress in the brain, offering support for cognitive clarity and long-term neurological protection.

Who Can Benefit from EGCG IV Therapy?

 

EGCG IV Therapy may be appropriate for individuals who:

  • Are managing chronic inflammation, autoimmune conditions, or pain syndromes

  • Want to slow aging at the cellular level and support detox pathways

  • Are pursuing weight loss or metabolic regulation

  • Have elevated liver enzymes or non-alcoholic fatty liver disease

  • Experience frequent oxidative stress from lifestyle, environmental exposure, or illness

  • Are looking to optimize cognitive function and reduce neuroinflammatory risk

This therapy is not recommended for individuals with uncontrolled bleeding disorders or very low blood pressure, as EGCG may affect platelet function.

How Is It Administered?

EGCG is delivered through a slow intravenous infusion, typically over 30 to 60 minutes, under medical supervision. This allows for controlled absorption and avoids gastrointestinal irritation commonly associated with high oral doses.

A typical protocol involves 1 session per week for 4–6 weeks, either as a standalone treatment or as part of a broader functional medicine program.

What to Expect During and After the Therapy

During the infusion, patients can relax in a comfortable setting while the therapy is administered by our clinical team. The treatment is well tolerated and painless, aside from the initial needle insertion.

Following treatment, patients often report:

  • A noticeable reduction in inflammatory symptoms such as joint stiffness or bloating

  • Improved mental clarity and energy

  • Better digestion and skin appearance over time

  • Enhanced metabolic balance with ongoing sessions

Most individuals experience no side effects. Mild headaches or light fatigue can occasionally occur as the body begins detoxification or adjusts to improved antioxidant activity.

Is EGCG IV Therapy Right for You?

If you’re seeking a natural yet scientifically backed approach to inflammation, detoxification, and cellular resilience, EGCG IV Therapy may offer the reset your system needs. Contact us to learn how this powerful green tea extract can be integrated into your personalized treatment plan.

References

  1. Yang, C. S., Wang, H., & Sheridan, Z. P. (2018).
    “Studies on prevention of obesity, metabolic syndrome, diabetes, cardiovascular diseases and cancer by tea.”
    Journal of Food and Drug Analysis, 26(1), 1–13.
    https://doi.org/10.1016/j.jfda.2017.10.005

  2. Mandel, S. A., et al. (2008).
    “Green tea catechins as brain-permeable, non-toxic iron chelators to ‘iron out iron’ from the brain.”
    Journal of Neural Transmission. Supplementum, (73), 249–257.
    https://doi.org/10.1007/978-3-211-09466-0_29

  3. Forester, S. C., & Lambert, J. D. (2011).
    “The role of antioxidant versus pro-oxidant effects of green tea polyphenols in cancer prevention.”
    Molecular Nutrition & Food Research, 55(6), 844–854.
    https://doi.org/10.1002/mnfr.201000641

  4. Kao, Y. H., Hiipakka, R. A., & Liao, S. (2000).
    “Modulation of endocrine systems and food intake by green tea epigallocatechin gallate.”
    Endocrinology, 141(3), 980–987.
    https://doi.org/10.1210/endo.141.3.7362

  5. Suganuma, M., et al. (2011).
    “Green tea polyphenols for prevention of lifestyle-related diseases.”
    BioFactors, 37(4), 254–260.
    https://doi.org/10.1002/biof.156