NAD+ IV Therapy: Restoring Cellular Energy and Slowing the Aging Process
- 24/02/2025
- Resources
- Dr Deepali Kapahi
Nicotinamide adenine dinucleotide (NAD⁺) is a vital coenzyme found in every cell of the human body, playing a central role in energy production, DNA repair, and metabolic regulation. However, NAD⁺ levels naturally decline with age, stress, illness, and environmental factors leading to reduced vitality and accelerated aging.
At Live More Clinic, NAD⁺ IV Therapy offers a direct and highly effective way to restore NAD⁺ levels, supporting optimal health, longevity, and performance.
What Is NAD⁺?
NAD⁺ is a coenzyme essential for mitochondrial energy production (ATP synthesis) and for the activation of key enzymes involved in cellular repair, known as sirtuins and PARPs. It supports nearly every aspect of metabolism and is critical for maintaining healthy aging processes.
When administered intravenously, NAD⁺ bypasses the gastrointestinal tract and enters the bloodstream directly, allowing for rapid and high-level replenishment of this essential molecule.

Key Benefits of NAD⁺ IV Therapy
Restored Energy and Mental Clarity
By enhancing mitochondrial function, NAD⁺ IV Therapy helps improve physical stamina, reduce fatigue, and boost mental clarity and focus. Many patients describe feeling a significant uplift in energy after a course of treatment.
Anti-Aging and Cellular Repair
NAD⁺ activates sirtuins—enzymes that regulate gene expression related to aging, inflammation, and metabolism. It also supports DNA repair processes, helping to slow biological aging at the cellular level.
Improved Metabolic Health
NAD⁺ plays a key role in glucose metabolism, insulin sensitivity, and fat oxidation. It can assist individuals managing metabolic syndrome, type 2 diabetes, or weight challenges.
Enhanced Neurological Function
Research indicates that NAD⁺ supports brain cell resilience, improves neuroplasticity, and may help reduce neuroinflammation. It is being explored as a supportive therapy in neurodegenerative diseases and cognitive decline.
Detoxification and Recovery
NAD⁺ helps regenerate glutathione, a major intracellular antioxidant involved in detoxification. It also aids in recovery from stress, illness, and substance use by promoting cellular repair and reducing oxidative stress.
Who Can Benefit from NAD⁺ IV Therapy?
NAD⁺ IV Therapy is ideal for individuals who:
Experience chronic fatigue or reduced physical stamina
Wish to slow biological aging and enhance longevity
Are managing cognitive decline, memory issues, or brain fog
Are undergoing detoxification or recovery programs
Are exposed to high stress or environmental toxins
Want to optimize performance, recovery, and resilience
While generally safe, NAD⁺ IV Therapy should be used with caution in individuals with severe cardiovascular instability or active cancer, under medical supervision.
How Is It Administered?
At Live More Clinic, NAD⁺ is administered as a slow intravenous infusion, typically over 1 to 1.5 hours, depending on the patient’s tolerance and dosage. This controlled delivery ensures that NAD⁺ is effectively taken up by the cells and utilized for metabolic processes.
A typical treatment protocol may include 1-2 sessions per week for 3-4 weeks, followed by maintenance infusions based on individual needs and goals.
What to Expect During and After the Therapy
During the infusion, some patients may experience transient sensations such as chest tightness, flushing, or light nausea. These are temporary and can be managed by adjusting the infusion rate.
After therapy, patients often report:
A marked increase in physical energy and endurance
Enhanced cognitive function and mental clarity
Improved mood and stress resilience
Faster recovery from exertion or illness
Results typically build over a course of treatments and can be sustained with periodic maintenance infusions.
Is NAD⁺ IV Therapy Right for You?
If you are seeking a science-backed therapy to restore energy, promote longevity, and support deep cellular repair, NAD⁺ IV Therapy offers a powerful tool for optimizing your health. Contact Live More Clinic to schedule a personalized consultation and explore how NAD⁺ can elevate your well-being.
References
Imai, S. I., & Guarente, L. (2014).
“NAD+ and sirtuins in aging and disease.”
Trends in Cell Biology, 24(8), 464–471.
https://doi.org/10.1016/j.tcb.2014.04.002Verdin, E. (2015).
“NAD+ in aging, metabolism, and neurodegeneration.”
Science, 350(6265), 1208–1213.
https://doi.org/10.1126/science.aac4854Grant, R., et al. (2019).
“NAD+ and NADH in cellular functions and cell death: Regulation and biological consequences.”
Cell Death and Disease, 10(8), 1–12.
https://doi.org/10.1038/s41419-019-1766-5Rajman, L., Chwalek, K., & Sinclair, D. A. (2018).
“Therapeutic potential of NAD+ precursors in aging and disease.”
Nature Reviews Drug Discovery, 17(7), 421–436.
https://doi.org/10.1038/nrd.2018.32Bogan, K. L., & Brenner, C. (2008).
“Nicotinamide riboside, a newly discovered NAD+ precursor.”
Journal of Nutrition, 138(12), 2297–2301.
https://doi.org/10.1093/jn/138.12.2297
Book Your Consultation
At Live More Phuket, we primarily use the NAD+ for Fighting against Aging to a cellular level and Increase energy levels and reduce Fatigue. We offer the best prices in Phuket for NAD+ Therapy, while using the highest quality medicines; we believe in fair and honest pricing.
Book a consultation with our specialists or visit our clinic to find out more, or browse our list of IV therapies here.